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SIDRA

GXB

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Description

Expression data from Treg subsets sorted from healthy human peripheral blood-GSE64176

Purpose

All the sorted Treg cells are gated on CD4+CD25+CD127(low), followed by gating on various subsets using markers indicated in the sample names.All the sorted Teff cells are gated on CD4+CD25-CD127(hi), and further sorted for CD45RO- and CD45RO+ phenotype.

Experimental Design

Each Treg and Teff cell subsets were sorted from three different donors. We sought to identify gene expression signature characteristic to specific Treg subsets

Additional Information
  • Hua J, Davis SP, Hill JA, Yamagata T. Diverse Gene Expression in Human Regulatory T Cell Subsets Uncovers Connection between Regulatory T Cell Genes and Suppressive Function. J Immunol 2015 Oct 15;195(8):3642-53. PMID: 26371251
  • Platform Affymetrix HuGene 1.0 ST v1
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    (Uploaded through the Files tab in the Annotation Tool)

    sampleset4000037_sampleannotations.csv

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