The role of vitamin D in the transcriptional program of human pregnancy-GSE86200

Peripheral whole blood transcriptome profiles of pregnant women enrolled in the “Vitamin D Antenatal Asthma Reduction Trial” (VDAART) at enrollment during early pregnancy, and again at 32-38 weeks of gestation. Mothers were enrolled in 2 treatment groups: Intervention group with 4400 IU vitamin D supplementation and Control group with 400 IU vitamin D supplementation.Comparing the whole blood (PAXgene) transcriptome profile of 30 mothers at enrollment during early pregnancy versus their matching individual profile at 32-38 weeks of gestation.

Whole blood transcriptome, dose response, time course, matched pair analysis

All 60 samples were standard background adjusted, logarithm base 2 transformed and quantile normalized using the R Bioconductor package lumi. Gene probes with empty gene symbols or unspecified chromosome locations were remove beforehand.

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE86200