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Clinical

The genomic architecture of host whole blood transcriptional response to malaria infection

Purpose

Analysis of the effect of malaria infection on whole blood gene expression and uncovering regulatory effects using eQTL analysis. Testing for relashionships between genotype, expression and malaria phenotypes.

Hypothesis

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Experimental Design

We generated whole blood gene expression profiles and genotypes from 155 West-African children including 94 cases undergoing the symptomatic phase of blood-stage Plasmodium falciparum infection and 61 age-matched controls. PCA, analysis of covariance and eQTL analysis were performed on the data.

Experimental Variables

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Controls

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Methods

The data were normalised using quantile normalisation with JMP Genomics

Additional Information

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34404

Microarray
Illumina HumanHT-12 v4
155 Samples Loaded: 155
Human (Homo sapiens)
Whole Blood
Malaria
RNA was extracted from whole blood collected in Tempus tubes using the Tempus Spin RNA Isolation kit (Applied Biosystems). Total RNA was then globin-mRNA-depleted using GlobinClear kit (Ambion). Quality control was performed with Agilent Bioanalyser.
Sample Set Spreadsheet
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Samples Preview
Sample ID Gender !Sample_title age (years) location white blood cells
GSM848438 M WB_B0001 10 Zinvie 9
GSM848439 F WB_B0002 2 Zinvie 10.5
GSM848440 M WB_B0003 8 Zinvie 9.7
GSM848441 F WB_B0004 7 Zinvie 8.9
GSM848442 F WB_B0005 4 Zinvie 9.3
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File
Quantile Normalized
Raw Signal
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Clinical Datasource
Links

Samples Viewer / Editor

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Sample ID Gender !Sample Title Age (years) Location White blood cells Parasitemia category Parasitemia Hemoglobin genotype Genotypic pc2 Genotypic pc1 Genotypic pc3 Sample name Malaria rd test Red blood cells Log2 parasitemia
GSM848438
M
WB_B0001
10
Zinvie
9
High Parasitemia
8747
AA
-0.1442
0.0491
-0.1143
PAW108
POSITIF
4
13.09
GSM848439
F
WB_B0002
2
Zinvie
10.5
Low Parasitemia
2368
AA
-0.0097
0.0859
-0.0108
PAW109
POSITIF
4.46
11.21
GSM848440
M
WB_B0003
8
Zinvie
9.7
Low Parasitemia
7905
AA
0.1207
0.087
-0.0534
PAW110
POSITIF
4.15
12.95
GSM848441
F
WB_B0004
7
Zinvie
8.9
High Parasitemia
13341
AA
-0.1442
0.0491
-0.1143
PAW111
POSITIF
3.26
13.70
GSM848442
F
WB_B0005
4
Zinvie
9.3
Low Parasitemia
8567
AA
-0.0026
0.1497
0.1454
PAW112
POSITIF
3.85
13.06
GSM848443
F
WB_B0006
1
Zinvie
10.3
High Parasitemia
23446
AC
0.0116
0.0203
0.0186
PAW113
POSITIF
4.84
14.52
GSM848444
F
WB_B0007
--
Zinvie
5.2
Low Parasitemia
1597
AA
-0.032
0.0678
-0.0742
PAW331
POSITIF
2.74
10.64
GSM848445
F
WB_B0008
8
Zinvie
11.3
Low Parasitemia
150
AA
-0.0251
0.0602
-0.0872
PAW114
POSITIF
4.07
7.23
GSM848446
M
WB_B0009
6
Zinvie
7.5
Low Parasitemia
180
AA
-0.0251
0.0602
-0.0872
PAW115
POSITIF
2.99
7.49
GSM848447
M
WB_B0010
6
Zinvie
6.7
Low Parasitemia
1600
AA
-0.3177
0.1799
-0.0019
PAW116
POSITIF
2.97
10.64
GSM848448
F
WB_B0011
4
Zinvie
10
High Parasitemia
22004
AA
0.0963
0.0246
-0.0779
PAW117
POSITIF
5.05
14.43
GSM848449
F
WB_B0012
6
Zinvie
6
Low Parasitemia
200
AA
-0.0251
0.0602
-0.0872
PAW118
POSITIF
2.66
7.64
GSM848450
M
WB_B0013
2
Zinvie
6
Low Parasitemia
1985
AA
0.1353
0.1135
0.1148
PAW119
POSITIF
3.42
10.95
GSM848451
M
WB_B0014
7
Zinvie
10.3
High Parasitemia
69638
AA
-0.3071
0.1296
-0.115
PAW120
POSITIF
4.82
16.09
GSM848452
F
WB_B0015
1
Zinvie
9.4
Low Parasitemia
210
AA
0.3472
0.227
-0.0116
PAW121
POSITIF
4
7.71
GSM848453
F
WB_B0016
4
Zinvie
6.2
High Parasitemia
23490
AC
0.0801
0.0101
-0.1189
PAW122
POSITIF
3.06
14.52
GSM848454
F
WB_B0017
6
Zinvie
9.9
Low Parasitemia
8190
AS
0.0287
0.2564
0.1191
PAW123
POSITIF
5.13
13.00
GSM848455
M
WB_B0018
6
Zinvie
8.8
High Parasitemia
46636
AA
-0.0227
0.1575
0.0226
PAW124
POSITIF
3.8
15.51
GSM848456
M
WB_B0019
5
Zinvie
4.9
Low Parasitemia
630
AA
0.1134
0.1718
-0.0228
PAW125
POSITIF
2.37
9.30
GSM848457
F
WB_B0020
4
Zinvie
10.7
Low Parasitemia
1213
AS
0.0133
0.0568
-0.049
PAW126
POSITIF
4
10.24
GSM848458
F
WB_B0021
7
Zinvie
10.9
High Parasitemia
43636
AA
--
--
--
PAW127
POSITIF
4.26
15.41
GSM848459
F
WB_B0022
5
Zinvie
6.9
Low Parasitemia
100
AA
-0.0326
0.0928
-0.0283
PAW128
POSITIF
3.51
6.64
GSM848460
F
WB_B0023
6
Zinvie
7.9
High Parasitemia
25188
AS
0.002
0.0724
0.1334
PAW129
POSITIF
3.56
14.62
GSM848461
M
WB_B0024
7
Zinvie
9.4
Low Parasitemia
275
AA
-0.0251
0.0602
-0.0872
PAW130
POSITIF
4.11
8.10
GSM848462
F
WB_B0026
4
Zinvie
7.7
Low Parasitemia
4320
AA
-0.0078
0.2749
0.2534
PAW333
POSITIF
3.14
12.08
GSM848463
F
WB_B0025
4
Zinvie
8.1
Low Parasitemia
4020
AA
-0.0069
0.2099
0.2411
PAW131
POSITIF
3.87
11.97
GSM848464
M
WB_B0027
1
Zinvie
10
High Parasitemia
168888
AA
-0.0085
-0.0141
0.0634
PAW132
POSITIF
5.02
17.37
GSM848465
M
WB_B0028
4
Zinvie
8.9
High Parasitemia
11851
AC
-0.0286
-0.0072
0.0683
PAW133
POSITIF
4.24
13.53
GSM848466
M
WB_B0029
2
Zinvie
7.2
Low Parasitemia
240
AA
0.332
0.33
0.0778
PAW134
POSITIF
3.06
7.91
GSM848467
M
WB_B0030
2
Zinvie
7.1
Low Parasitemia
120
AS
0.0482
0.1541
0.0912
PAW135
POSITIF
3.12
6.91
GSM848468
F
WB_B0031
4
Zinvie
4.3
High Parasitemia
20230
AA
-0.0221
0.0779
0.0425
PAW136
POSITIF
1.96
14.30
GSM848469
F
WB_B0032
2
Zinvie
4.5
Low Parasitemia
3222
AA
0.2371
-0.0079
-0.262
PAW137
POSITIF
1.91
11.65
GSM848470
F
WB_B0033
6
Zinvie
8.5
High Parasitemia
181714
AA
-0.2958
0.2071
-0.1016
PAW334
POSITIF
3.35
17.47
GSM848471
F
WB_B0034
2
Zinvie
6.5
High Parasitemia
100000
AA
-0.0856
0.1131
-0.0942
PAW335
POSITIF
2.79
16.61
GSM848472
F
WB_B0035
7
Zinvie
8.2
Low Parasitemia
3407
AA
0.0651
0.0409
-0.0869
PAW138
POSITIF
3.49
11.73
GSM848473
M
WB_B0036
5
Zinvie
10.5
Low Parasitemia
3352
AA
0.0899
0.0193
-0.0872
PAW139
POSITIF
4.23
11.71
GSM848474
F
WB_B0037
2
Zinvie
9.1
High Parasitemia
34950
AA
0.0714
-0.0652
-0.0563
PAW140
POSITIF
5.4
15.09
GSM848475
F
WB_B0038
4
Zinvie
10.8
Low Parasitemia
300
AS
0.0819
-0.0668
-0.0812
PAW336
POSITIF
4.75
8.23
GSM848476
F
WB_B0039
2
Zinvie
9.9
High Parasitemia
30377
AA
0.0714
-0.0652
-0.0563
PAW337
POSITIF
4.36
14.89
GSM848477
F
WB_B0040
6
Zinvie
9.1
Low Parasitemia
360
AA
0.204
0.2269
-0.0328
PAW141
POSITIF
4.29
8.49
GSM848478
M
WB_B0041
4
Zinvie
8.1
Low Parasitemia
6360
AA
--
--
--
PAW338
POSITIF
2.74
12.63
GSM848479
F
WB_B0043
4
Zinvie
7.4
Low Parasitemia
600
AA
-0.0343
-0.009
-0.2325
PAW142
POSITIF
3.12
9.23
GSM848480
F
WB_B0044
3
Zinvie
11.2
Low Parasitemia
634
AC
0.0969
-0.0446
-0.0747
PAW143
POSITIF
4.47
9.31
GSM848481
M
WB_B0045
5
Zinvie
9.5
High Parasitemia
29000
AS
0.0695
-0.0245
-0.2165
PAW340
POSITIF
4.03
14.82
GSM848482
M
WB_B0046
3
Zinvie
9.7
Low Parasitemia
7351
AA
-0.0227
0.1575
0.0226
PAW144
POSITIF
3.96
12.84
GSM848483
M
WB_B0047
6
Zinvie
7.4
High Parasitemia
31843
AC
0.0028
0.0028
-0.0377
PAW145
POSITIF
3.4
14.96
GSM848484
F
WB_B0048
4
Zinvie
9.1
High Parasitemia
12428
AA
-0.0078
0.2749
0.2534
PAW146
POSITIF
4.5
13.60
GSM848485
F
WB_B0049
4
Zinvie
10.5
Low Parasitemia
540
AA
0.0133
0.0568
-0.049
PAW147
POSITIF
4.32
9.08
GSM848486
F
WB_B0050
2
Zinvie
7.6
Low Parasitemia
3226
AA
-0.278
0.2695
-0.0485
PAW148
POSITIF
3.78
11.66
GSM848487
M
WB_B0051
--
Zinvie
10.4
High Parasitemia
181406
AA
-0.1059
0.1438
-0.1078
PAW341
POSITIF
4.27
17.47
GSM848488
M
WB_B0052
3
Zinvie
9.2
High Parasitemia
102500
AA
-0.1327
0.1219
-0.2502
PAW342
POSITIF
4.94
16.65
GSM848489
M
WB_B0053
4
Zinvie
8.2
High Parasitemia
115600
AS
-0.0227
0.1575
0.0226
PAW343
POSITIF
3.57
16.82
GSM848490
M
WB_B0054
3
Zinvie
9.5
High Parasitemia
644000
AC
0.0061
-0.0005
0
PAW149
POSITIF
5.02
19.30
GSM848491
M
WB_B0055
1
Zinvie
10.4
High Parasitemia
660400
AC
-0.0188
-0.0244
0.0551
PAW344
POSITIF
5.34
19.33
GSM848492
F
WB_B0056
2
Zinvie
--
Low Parasitemia
120
AA
-0.278
0.2695
-0.0485
PAW345
NEGATIF
--
6.91
GSM848493
F
WB_C0001
3
Cotonou
3.8
Low Parasitemia
120
AA
0.0223
-0.0053
-0.0734
PAW346
POSITIF
1.73
6.91
GSM848494
F
WB_C0002
3
Cotonou
4.7
High Parasitemia
50000
AA
0.0617
-0.0172
-0.0655
PAW150
POSITIF
0.05
15.61
GSM848495
M
WB_C0003
3
Cotonou
3.8
High Parasitemia
70000
AA
-0.0133
-0.0392
0.0816
PAW347
POSITIF
1.58
16.10
GSM848496
F
WB_C0004
5
Cotonou
5.5
High Parasitemia
36000
AC
-0.0181
-0.0526
-0.0279
PAW151
POSITIF
2.33
15.14
GSM848497
F
WB_C0005
2
Cotonou
10
High Parasitemia
20000
AA
0.0379
-0.0741
-0.0414
PAW152
POSITIF
4.2
14.29
GSM848498
M
WB_C0006
2
Cotonou
5.5
Low Parasitemia
2500
AA
0.0859
-0.0431
-0.1026
PAW153
POSITIF
2.49
11.29
GSM848499
M
WB_C0007
3
Cotonou
4
High Parasitemia
20000
AA
-0.0869
-0.0155
0.0309
PAW154
POSITIF
1.79
14.29
GSM848500
F
WB_C0008
2
Cotonou
7
Low Parasitemia
3200
AC
0.0618
-0.0571
-0.0529
PAW155
POSITIF
4.11
11.64
GSM848501
M
WB_C0009
2
Cotonou
9.3
High Parasitemia
370000
AA
-0.0033
-0.0284
0.0001
PAW348
POSITIF
4
18.50
GSM848502
F
WB_C0010
2
Cotonou
10.5
Low Parasitemia
230
AA
-0.052
-0.0146
-0.0408
PAW156
POSITIF
4.1
7.85
GSM848503
F
WB_C0011
1
Cotonou
11.9
Low Parasitemia
1800
AA
-0.0019
-0.0615
0.1037
PAW157
POSITIF
4.4
10.81
GSM848504
M
WB_C0012
1
Cotonou
7.4
High Parasitemia
120000
AA
-0.0252
-0.0418
0.022
PAW158
POSITIF
2.8
16.87
GSM848505
M
WB_C0013
4
Cotonou
4.2
Low Parasitemia
600
AA
-0.1174
0.0651
-0.0355
PAW159
POSITIF
1.9
9.23
GSM848506
M
WB_C0014
2
Cotonou
11.1
High Parasitemia
89586
AA
0.023
-0.0254
-0.0642
PAW160
POSITIF
5.02
16.45
GSM848507
F
WB_C0016
4
Cotonou
8.3
Low Parasitemia
4747
AA
-0.0228
-0.0663
0.0663
PAW349
POSITIF
3.01
12.21
GSM848508
F
WB_C0015
4
Cotonou
7.6
Low Parasitemia
4500
AA
-0.0119
-0.0563
0.0701
PAW161
POSITIF
3.15
12.14
GSM848509
F
WB_C0017
4
Cotonou
2.6
Low Parasitemia
150
AA
0.0316
-0.1156
0.0298
PAW162
POSITIF
0.62
7.23
GSM848510
F
WB_C0018
6
Cotonou
10.6
High Parasitemia
65555
AC
-0.0048
-0.0419
0.0119
PAW163
POSITIF
4.8
16.00
GSM848511
F
WB_C0019
4
Cotonou
6.4
High Parasitemia
229200
AA
0.0717
-0.057
-0.0126
PAW164
POSITIF
2.7
17.81
GSM848512
M
WB_C0020
5
Cotonou
5.5
High Parasitemia
72600
AA
-0.0531
-0.0304
0.0022
PAW480
POSITIF
3.3
16.15
GSM848513
M
WB_C0021
2
Cotonou
2.4
Low Parasitemia
1200
AA
-0.0194
-0.0619
-0.0238
PAW481
POSITIF
1
10.23
GSM848514
M
WB_C0022
6
Cotonou
7
Low Parasitemia
263
AA
-0.025
-0.0823
0.0768
PAW482
POSITIF
2.7
8.04
GSM848515
M
WB_C0023
5
Cotonou
12.2
Low Parasitemia
300
AA
-0.0606
-0.0368
-0.0253
PAW483
POSITIF
5.02
8.23
GSM848516
F
WB_C0024
3
Cotonou
3.7
High Parasitemia
340800
AC
-0.0271
-0.0935
0.1051
PAW484
POSITIF
2
18.38
GSM848517
M
WB_C0025
3
Cotonou
7
High Parasitemia
38920
AS
0.0058
-0.0581
0.106
PAW485
POSITIF
3.4
15.25
GSM848518
F
WB_C0026
3
Cotonou
3.4
Low Parasitemia
860
AA
0.0251
-0.0397
-0.0112
PAW486
POSITIF
1
9.75
GSM848519
M
WB_C0027
2
Cotonou
7.8
Low Parasitemia
1280
AS
0.0223
-0.056
-0.0345
PAW487
POSITIF
3
10.32
GSM848520
F
WB_C0028
3
Cotonou
2.3
High Parasitemia
26760
AA
0.0059
-0.0642
0.008
PAW488
POSITIF
1
14.71
GSM848521
M
WB_C0029
6
Cotonou
10.7
Low Parasitemia
5180
AA
-0.0166
-0.0782
0.0207
PAW489
POSITIF
5
12.34
GSM848522
F
WB_C0030
3
Cotonou
3.9
High Parasitemia
77513
AA
-0.0056
-0.0003
-0.0285
PAW490
POSITIF
1
16.24
GSM848523
F
WB_C0031
5
Cotonou
11.9
Low Parasitemia
2860
AA
0.0306
-0.052
-0.0924
PAW491
POSITIF
5
11.48
GSM848524
M
WB_C0032
5
Cotonou
5.4
High Parasitemia
63103
AA
-0.0008
-0.0632
0.0077
PAW492
POSITIF
2
15.95
GSM848525
M
WB_C0033
4
Cotonou
11.2
Low Parasitemia
210
AA
0.0306
0.0033
0.0502
PAW493
POSITIF
4
7.71
GSM848526
M
WB_C0034
1
Cotonou
2.1
Low Parasitemia
5769
AA
-0.0268
-0.0587
0.0802
PAW494
POSITIF
1
12.49
GSM848527
M
WB_C0035
3
Cotonou
7.3
Low Parasitemia
4409
AA
0.0262
-0.0035
0.0955
PAW495
POSITIF
1.17
12.11
GSM848528
F
WB_C0036
4
Cotonou
8
High Parasitemia
420000
AA
-0.035
-0.0292
0.0723
PAW496
POSITIF
3.4
18.68
GSM848529
F
WB_C0037
5
Cotonou
3.1
Low Parasitemia
660
AA
-0.0283
-0.0616
-0.0131
PAW497
POSITIF
1
9.37
GSM848530
M
WB_C0038
6
Cotonou
2.7
High Parasitemia
96872
AA
-0.0489
-0.0322
0.1209
PAW498
POSITIF
1
16.56
GSM848531
F
WB_C0039
1
Cotonou
3
Low Parasitemia
1081
AA
0.0276
0.0467
0.0843
PAW499
POSITIF
1
10.08
GSM848532
M
WB_HFS101
5
Cotonou
11.1
C
0
AS
-0.025
-0.043
0.0019
PAW500
NEGATIF
4.67
0.00
GSM848533
M
WB_HFS105
5
Cotonou
10.9
C
0
AA
-0.0507
-0.0147
0.1053
PAW501
NEGATIF
4.58
0.00
GSM848534
F
WB_HFS106
5
Cotonou
10.9
C
0
AS
-0.0098
0.0115
0.0097
PAW502
NEGATIF
4.46
0.00
GSM848535
F
WB_HFS109
4
Cotonou
11.6
C
0
AS
-0.0072
-0.0313
-0.0068
PAW504
NEGATIF
4.64
0.00
GSM848536
F
WB_HFS110
2
Cotonou
11
C
0
AS
0.0253
-0.0107
-0.0292
PAW505
NEGATIF
4.82
0.00
GSM848537
F
WB_HFS111
3
Cotonou
9.9
C
0
AS
-0.0262
-0.0343
-0.1022
PAW506
NEGATIF
4.29
0.00
GSM848538
F
WB_HFS112
1
Cotonou
10
C
0
AS
0.0371
0.0043
-0.0503
PAW507
NEGATIF
4.81
0.00
GSM848539
M
WB_HFS113
1
Cotonou
10.5
C
0
AS
-0.0384
-0.0428
-0.0087
PAW508
NEGATIF
5.33
0.00
GSM848540
M
WB_HFS114
2
Cotonou
11.1
C
0
AS
-0.0438
-0.0516
0.136
PAW509
NEGATIF
4.42
0.00
GSM848541
M
WB_HFS115
6
Cotonou
10.9
C
0
AA
0.0517
-0.0322
0.0806
PAW510
NEGATIF
5.6
0.00
GSM848542
M
WB_HFS116
2
Cotonou
8.9
C
0
AC
-0.0052
-0.0095
0.1696
PAW511
NEGATIF
3.45
0.00
GSM848543
F
WB_HFS117
3
Cotonou
7.2
C
0
AS
0.0396
-0.0371
-0.0939
PAW512
NEGATIF
3.03
0.00
GSM848544
F
WB_HFS118
2
Cotonou
11.8
C
0
AS
-0.0432
-0.084
-0.0695
PAW513
NEGATIF
5.22
0.00
GSM848545
M
WB_HFS119
3
Cotonou
10
C
0
AA
0.0029
0.0075
-0.0231
PAW514
NEGATIF
5.35
0.00
GSM848546
M
WB_HFS120
1
Cotonou
9.8
C
0
AS
-0.03
-0.0637
-0.0484
PAW515
NEGATIF
5.34
0.00
GSM848547
M
WB_HFS122
1
Cotonou
8.4
C
0
AA
-0.0798
-0.0575
0.003
PAW517
NEGATIF
4.55
0.00
GSM848548
F
WB_HFS124
1
Cotonou
10.4
C
0
AA
0.0094
-0.0065
-0.0029
PAW518
NEGATIF
4.31
0.00
GSM848549
M
WB_HFS126
1
Cotonou
8.2
C
0
AC
0.0146
0.0093
-0.0063
PAW519
NEGATIF
3.77
0.00
GSM848550
F
WB_HFS127
2
Cotonou
10.7
C
0
AS
0.0742
-0.0312
-0.0766
PAW520
NEGATIF
4.92
0.00
GSM848551
M
WB_HFS129
3
Cotonou
10.2
C
0
AS
-0.025
-0.0675
-0.0181
PAW522
NEGATIF
5.31
0.00
GSM848552
F
WB_HFS130
3
Cotonou
11.1
C
0
AA
-0.0441
-0.0357
0.0942
PAW523
NEGATIF
4.87
0.00
GSM848553
F
WB_HFS131
3
Cotonou
10.8
C
0
AS
--
--
--
PAW524
NEGATIF
4.9
0.00
GSM848554
M
WB_HFS132
5
Cotonou
10.5
C
0
AS
0.0342
-0.0453
-0.0731
PAW525
NEGATIF
4.67
0.00
GSM848555
F
WB_HFS134
5
Cotonou
10.1
C
0
AS
0.0333
0.0134
0.0471
PAW526
NEGATIF
5.07
0.00
GSM848556
F
WB_HFS135
3
Cotonou
11.9
C
0
AA
-0.0284
-0.0613
0.0043
PAW527
NEGATIF
4.97
0.00
GSM848557
M
WB_HFS136
2
Cotonou
11.1
C
0
AS
0.0141
-0.0273
-0.03
PAW528
NEGATIF
4.97
0.00
GSM848558
M
WB_HFS137
2
Cotonou
10.1
C
0
AS
-0.0101
-0.075
0.0098
PAW529
NEGATIF
4.39
0.00
GSM848559
F
WB_HFS138
5
Cotonou
11.1
C
0
AS
-0.0275
-0.025
0.0561
PAW530
NEGATIF
4.48
0.00
GSM848560
M
WB_HFS139
5
Cotonou
10.2
C
0
AS
0.0329
-0.0686
0.0677
PAW531
NEGATIF
5.18
0.00
GSM848561
F
WB_HFS140
5
Cotonou
12.3
C
0
AS
--
--
--
PAW532
NEGATIF
4.87
0.00
GSM848562
F
WB_HFS141
1
Cotonou
11.3
C
0
AS
0.0257
-0.031
-0.0856
PAW533
NEGATIF
4.51
0.00
GSM848563
F
WB_HFS143
2
Cotonou
11.6
C
0
AA
-0.0199
0.089
0.151
PAW534
NEGATIF
4.89
0.00
GSM848564
F
WB_HFS144
1
Cotonou
10
C
0
AS
-0.005
-0.0274
0.1015
PAW535
NEGATIF
5.97
0.00
GSM848565
F
WB_HFS145
2
Cotonou
10.9
C
0
AS
--
--
--
PAW536
NEGATIF
4.79
0.00
GSM848566
M
WB_HFS146
6
Cotonou
12.8
C
0
AS
-0.0005
-0.084
0.1038
PAW537
NEGATIF
4.8
0.00
GSM848567
M
WB_HFS147
2
Cotonou
7
C
0
AC
-0.0041
-0.0408
0.0094
PAW538
NEGATIF
2.53
0.00
GSM848568
M
WB_HFS148
3
Cotonou
12.1
C
0
AS
0.0231
-0.0361
0.1176
PAW539
NEGATIF
5.3
0.00
GSM848569
F
WB_HFS149
2
Cotonou
12
C
0
AS
0.0447
-0.0798
0.0072
PAW540
NEGATIF
5.41
0.00
GSM848570
F
WB_HFS150
3
Cotonou
11.9
C
0
AA
0.0279
-0.0008
0.1038
PAW541
NEGATIF
5.18
0.00
GSM848571
F
WB_HFS151
3
Cotonou
12.2
C
0
AS
-0.0053
0.0112
-0.1215
PAW542
NEGATIF
5.15
0.00
GSM848572
M
WB_HFS152
1
Cotonou
10.8
C
0
AA
-0.0364
-0.0512
0.0415
PAW543
NEGATIF
4.42
0.00
GSM848573
F
WB_HFS153
1
Cotonou
10.4
C
0
AS
-0.0283
-0.0303
0.1533
PAW544
NEGATIF
4.44
0.00
GSM848574
F
WB_HFS154
4
Cotonou
12.2
C
0
AS
-0.045
-0.0459
0.1086
PAW545
NEGATIF
4.37
0.00
GSM848575
F
WB_HFS156
6
Cotonou
10.9
C
0
AS
--
--
--
PAW546
NEGATIF
4.38
0.00
GSM848576
M
WB_HFS157
5
Cotonou
11.6
C
0
AS
-0.01
-0.0329
0.0896
PAW547
NEGATIF
5.26
0.00
GSM848577
M
WB_HFS158
3
Cotonou
11.5
C
0
AA
0.0784
-0.0339
0.0351
PAW548
NEGATIF
4.86
0.00
GSM848578
F
WB_HFS159
2
Cotonou
11.9
C
0
AS
-0.0601
-0.0545
0.0042
PAW549
NEGATIF
4.8
0.00
GSM848579
F
WB_HFS160
3
Cotonou
7.3
C
0
AC
0.015
-0.0802
0.05
PAW550
NEGATIF
2.92
0.00
GSM848580
F
WB_HFS161
3
Cotonou
10.7
C
0
AS
0.0481
-0.0447
-0.0684
PAW551
NEGATIF
4.5
0.00
GSM848581
F
WB_HFS162
5
Cotonou
11.5
C
0
AA
0.036
-0.1346
0.0968
PAW552
NEGATIF
5.36
0.00
GSM848582
F
WB_HFS163
1
Cotonou
9.9
C
0
AS
-0.0327
-0.0632
0.0215
PAW553
NEGATIF
3.8
0.00
GSM848583
M
WB_HFS164
2
Cotonou
10.8
C
0
AS
0.0345
-0.0281
-0.0795
PAW554
NEGATIF
5.38
0.00
GSM848584
F
WB_HFS165
3
Cotonou
11.2
C
0
AA
0.022
-0.0257
-0.0962
PAW555
NEGATIF
4.83
0.00
GSM848585
F
WB_HFS166
2
Cotonou
11.4
C
0
AA
-0.1052
-0.0637
0.0083
PAW556
NEGATIF
5.05
0.00
GSM848586
M
WB_HFS167
1
Cotonou
10.8
C
0
AS
0.0183
-0.036
-0.0127
PAW557
NEGATIF
4.82
0.00
GSM848587
M
WB_HFS168
4
Cotonou
10.3
C
0
AS
-0.0062
-0.037
0.1378
PAW558
NEGATIF
4.91
0.00
GSM848588
M
WB_HFS169
6
Cotonou
12.8
C
0
AA
-0.0228
-0.0791
-0.0391
PAW559
NEGATIF
4.42
0.00
GSM848589
F
WB_HFS170
1
Cotonou
11.4
C
0
AS
-0.0517
-0.0262
-0.0833
PAW560
NEGATIF
4.95
0.00
GSM848590
M
WB_HFS171
6
Cotonou
11.2
C
0
AS
0.0072
-0.0669
-0.0647
PAW561
NEGATIF
4.5
0.00
GSM848591
F
WB_HFS172
1
Cotonou
11.7
C
0
AA
-0.0336
-0.0561
-0.0063
PAW562
NEGATIF
4.43
0.00
GSM848592
M
WB_HFS173
2
Cotonou
11
C
0
AA
-0.0078
-0.0875
0.0696
PAW563
NEGATIF
4.75
0.00

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