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Clinical

Maternal Whole Blood Gene Expression at 18 and 28 weeks of Gestation Associated with Spontaneous Preterm Birth in Asymptomatic Women-GSE59491

Purpose

To investigate maternal whole blood gene expression profiles associated with spontaneous preterm birth (SPTB, <37 weeks) in asymptomatic pregnant women.The ‘All Our Babies’ (AOB) community based cohort in Calgary recruited pregnant women between May 2008 and December 2010.

Hypothesis

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Experimental Design

Maternal blood at 17-23 (time point 1, T1) and 27-33 weeks of gestation (T2) were collected. Fifty-one SPTBs were matched to 114 term delivery controls.Microarray was performed on 326 samples from 165 women. Univariate analyses determined significant clinical factors and differential gene expression associated with SPTB. Thirteen genes were validated using qRT-PCR.Three multivariate models were constructed to identify gene expressions associated with SPTB at T1 (Model A) and T2 (Model B), and temporal gene expressions (T2-T1) associated with SPTB at T2 (Model C).

Experimental Variables

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Controls

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Methods
Data were normalized using RMA and differential expression was determined using Limma with multiple hypothesis testing (Benjamini and Hochberg); Bioconductor, R
Additional Information

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE59491

Microarray
Affymetrix HuGene_2_1_st v1
326 Samples Loaded: 326
Human (Homo sapiens)
Whole Blood
Pregnancy
Sample collection protocol: Peripheral maternal blood collected using PAXgene tubes. PAXgene Blood RNA system kit was used to isolate total RNA.
Sample Set Spreadsheet
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Samples Preview
Sample ID !Sample_title tissue gest age at sampling (weeks) birthing outcome (sptl 1, pprom 2, term 3) gest age at delivery (weeks)
GSM1437801 wholeblood_515122_1 peripheral maternal blood 19 3 40
GSM1437802 wholeblood_515122_2 peripheral maternal blood 28 3 40
GSM1437803 wholeblood_810384_1 peripheral maternal blood 18 3 40
GSM1437804 wholeblood_810384_2 peripheral maternal blood 28 3 40
GSM1437805 wholeblood_810392_1 peripheral maternal blood 18 3 41
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Raw Signal
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Sample ID !Sample Title Tissue Gest age at sampling (weeks) Birthing outcome (sptl 1, pprom 2, term 3) Gest age at delivery (weeks) Sample collected at time pt (17-23weeks 1, 27-33weeks 2) Birth outcome (sptb 1, term 0) Individual id
GSM1437801
wholeblood_515122_1
peripheral maternal blood
19
3
40
1
0
515122
GSM1437802
wholeblood_515122_2
peripheral maternal blood
28
3
40
2
0
515122
GSM1437803
wholeblood_810384_1
peripheral maternal blood
18
3
40
1
0
810384
GSM1437804
wholeblood_810384_2
peripheral maternal blood
28
3
40
2
0
810384
GSM1437805
wholeblood_810392_1
peripheral maternal blood
18
3
41
1
0
810392
GSM1437806
wholeblood_810392_2A
peripheral maternal blood
28
3
41
2
0
810392
GSM1437807
wholeblood_810401_1
peripheral maternal blood
20
3
40
1
0
810401
GSM1437808
wholeblood_810401_2
peripheral maternal blood
30
3
40
2
0
810401
GSM1437809
wholeblood_810413_1
peripheral maternal blood
20
1
35
1
1
810413
GSM1437810
wholeblood_810413_2
peripheral maternal blood
28
1
35
2
1
810413
GSM1437811
wholeblood_810416_1
peripheral maternal blood
20
3
38
1
0
810416
GSM1437812
wholeblood_810416_2
peripheral maternal blood
32
3
38
2
0
810416
GSM1437813
wholeblood_810421_1
peripheral maternal blood
20
3
40
1
0
810421
GSM1437814
wholeblood_810421_2
peripheral maternal blood
27
3
40
2
0
810421
GSM1437815
wholeblood_810424_1
peripheral maternal blood
18
3
40
1
0
810424
GSM1437816
wholeblood_810424_2
peripheral maternal blood
28
3
40
2
0
810424
GSM1437817
wholeblood_810430_1
peripheral maternal blood
21
3
39
1
0
810430
GSM1437818
wholeblood_810430_2C
peripheral maternal blood
28
3
39
2
0
810430
GSM1437819
wholeblood_810432_1
peripheral maternal blood
18
3
39
1
0
810432
GSM1437820
wholeblood_810432_2
peripheral maternal blood
29
3
39
2
0
810432
GSM1437821
wholeblood_810439_1B
peripheral maternal blood
18
3
40
1
0
810439
GSM1437822
wholeblood_810439_2A
peripheral maternal blood
30
3
40
2
0
810439
GSM1437823
wholeblood_810447_1
peripheral maternal blood
19
3
38
1
0
810447
GSM1437824
wholeblood_810447_2
peripheral maternal blood
27
3
38
2
0
810447
GSM1437825
wholeblood_810460_1
peripheral maternal blood
18
3
38
1
0
810460
GSM1437826
wholeblood_810460_2
peripheral maternal blood
29
3
38
2
0
810460
GSM1437827
wholeblood_810462_1
peripheral maternal blood
19
3
40
1
0
810462
GSM1437828
wholeblood_810462_2
peripheral maternal blood
29
3
40
2
0
810462
GSM1437829
wholeblood_810469_1
peripheral maternal blood
19
3
38
1
0
810469
GSM1437830
wholeblood_810469_2
peripheral maternal blood
28
3
38
2
0
810469
GSM1437831
wholeblood_810477_1
peripheral maternal blood
19
1
27
1
1
810477
GSM1437832
wholeblood_810494_1
peripheral maternal blood
18
3
37
1
0
810494
GSM1437833
wholeblood_810494_2
peripheral maternal blood
28
3
37
2
0
810494
GSM1437834
wholeblood_810501_1
peripheral maternal blood
20
3
38
1
0
810501
GSM1437835
wholeblood_810501_2
peripheral maternal blood
29
3
38
2
0
810501
GSM1437836
wholeblood_810507_1
peripheral maternal blood
20
3
40
1
0
810507
GSM1437837
wholeblood_810507_2
peripheral maternal blood
30
3
40
2
0
810507
GSM1437838
wholeblood_810516_1
peripheral maternal blood
20
3
40
1
0
810516
GSM1437839
wholeblood_810516_2
peripheral maternal blood
29
3
40
2
0
810516
GSM1437840
wholeblood_810518_1
peripheral maternal blood
21
3
38
1
0
810518
GSM1437841
wholeblood_810518_2
peripheral maternal blood
28
3
38
2
0
810518
GSM1437842
wholeblood_810521_1
peripheral maternal blood
19
3
41
1
0
810521
GSM1437843
wholeblood_810521_2
peripheral maternal blood
28
3
41
2
0
810521
GSM1437844
wholeblood_810529_1
peripheral maternal blood
19
2
33
1
1
810529
GSM1437845
wholeblood_810529_2
peripheral maternal blood
29
2
33
2
1
810529
GSM1437846
wholeblood_810533_1
peripheral maternal blood
19
3
41
1
0
810533
GSM1437847
wholeblood_810533_2
peripheral maternal blood
30
3
41
2
0
810533
GSM1437848
wholeblood_810545_1
peripheral maternal blood
18
3
39
1
0
810545
GSM1437849
wholeblood_810545_2
peripheral maternal blood
30
3
39
2
0
810545
GSM1437850
wholeblood_810563_1
peripheral maternal blood
22
3
40
1
0
810563
GSM1437851
wholeblood_810563_2
peripheral maternal blood
28
3
40
2
0
810563
GSM1437852
wholeblood_810568_1
peripheral maternal blood
20
3
40
1
0
810568
GSM1437853
wholeblood_810568_2
peripheral maternal blood
31
3
40
2
0
810568
GSM1437854
wholeblood_810619_1
peripheral maternal blood
19
3
38
1
0
810619
GSM1437855
wholeblood_810619_2
peripheral maternal blood
28
3
38
2
0
810619
GSM1437856
wholeblood_810657_1
peripheral maternal blood
19
1
35
1
1
810657
GSM1437857
wholeblood_810657_2
peripheral maternal blood
32
1
35
2
1
810657
GSM1437858
wholeblood_812226_1
peripheral maternal blood
18
3
37
1
0
812226
GSM1437859
wholeblood_812226_2
peripheral maternal blood
29
3
37
2
0
812226
GSM1437860
wholeblood_812228_1
peripheral maternal blood
18
1
34
1
1
812228
GSM1437861
wholeblood_812228_2
peripheral maternal blood
29
1
34
2
1
812228
GSM1437862
wholeblood_812230_1
peripheral maternal blood
19
3
38
1
0
812230
GSM1437863
wholeblood_812230_2
peripheral maternal blood
30
3
38
2
0
812230
GSM1437864
wholeblood_812232_1
peripheral maternal blood
20
3
40
1
0
812232
GSM1437865
wholeblood_812232_2
peripheral maternal blood
31
3
40
2
0
812232
GSM1437866
wholeblood_812234_1
peripheral maternal blood
19
3
38
1
0
812234
GSM1437867
wholeblood_812234_2
peripheral maternal blood
29
3
38
2
0
812234
GSM1437868
wholeblood_812235_1
peripheral maternal blood
19
3
40
1
0
812235
GSM1437869
wholeblood_812235_2
peripheral maternal blood
28
3
40
2
0
812235
GSM1437870
wholeblood_812236_1
peripheral maternal blood
19
3
39
1
0
812236
GSM1437871
wholeblood_812236_2
peripheral maternal blood
28
3
39
2
0
812236
GSM1437872
wholeblood_812249_1
peripheral maternal blood
21
3
41
1
0
812249
GSM1437873
wholeblood_812249_2
peripheral maternal blood
32
3
41
2
0
812249
GSM1437874
wholeblood_812261_1
peripheral maternal blood
18
3
41
1
0
812261
GSM1437875
wholeblood_812261_2
peripheral maternal blood
28
3
41
2
0
812261
GSM1437876
wholeblood_812268_1
peripheral maternal blood
19
3
39
1
0
812268
GSM1437877
wholeblood_812268_2
peripheral maternal blood
28
3
39
2
0
812268
GSM1437878
wholeblood_812282_1
peripheral maternal blood
20
2
29
1
1
812282
GSM1437879
wholeblood_812285_1
peripheral maternal blood
21
1
34
1
1
812285
GSM1437880
wholeblood_812285_2
peripheral maternal blood
31
1
34
2
1
812285
GSM1437881
wholeblood_812292_1
peripheral maternal blood
19
3
40
1
0
812292
GSM1437882
wholeblood_812292_2
peripheral maternal blood
31
3
40
2
0
812292
GSM1437883
wholeblood_812296_1
peripheral maternal blood
19
3
39
1
0
812296
GSM1437884
wholeblood_812296_2
peripheral maternal blood
30
3
39
2
0
812296
GSM1437885
wholeblood_812302_1
peripheral maternal blood
19
2
29
1
1
812302
GSM1437886
wholeblood_812302_2
peripheral maternal blood
28
2
29
2
1
812302
GSM1437887
wholeblood_812309_1
peripheral maternal blood
19
1
32
1
1
812309
GSM1437888
wholeblood_812309_2
peripheral maternal blood
30
1
32
2
1
812309
GSM1437889
wholeblood_812324_1
peripheral maternal blood
20
3
40
1
0
812324
GSM1437890
wholeblood_812324_2
peripheral maternal blood
30
3
40
2
0
812324
GSM1437891
wholeblood_812329_1
peripheral maternal blood
18
3
39
1
0
812329
GSM1437892
wholeblood_812329_2
peripheral maternal blood
29
3
39
2
0
812329
GSM1437893
wholeblood_812342_1
peripheral maternal blood
19
2
36
1
1
812342
GSM1437894
wholeblood_812342_2
peripheral maternal blood
29
2
36
2
1
812342
GSM1437895
wholeblood_812344_1
peripheral maternal blood
22
3
42
1
0
812344
GSM1437896
wholeblood_812344_2
peripheral maternal blood
32
3
42
2
0
812344
GSM1437897
wholeblood_812359_1
peripheral maternal blood
21
2
36
1
1
812359
GSM1437898
wholeblood_812359_2
peripheral maternal blood
28
2
36
2
1
812359
GSM1437899
wholeblood_812366_1
peripheral maternal blood
19
3
39
1
0
812366
GSM1437900
wholeblood_812366_2
peripheral maternal blood
27
3
39
2
0
812366
GSM1437901
wholeblood_812387_1
peripheral maternal blood
19
3
39
1
0
812387
GSM1437902
wholeblood_812387_2
peripheral maternal blood
29
3
39
2
0
812387
GSM1437903
wholeblood_812396_1
peripheral maternal blood
19
3
39
1
0
812396
GSM1437904
wholeblood_812396_2
peripheral maternal blood
29
3
39
2
0
812396
GSM1437905
wholeblood_812407_1
peripheral maternal blood
19
3
37
1
0
812407
GSM1437906
wholeblood_812407_2
peripheral maternal blood
29
3
37
2
0
812407
GSM1437907
wholeblood_812448_1
peripheral maternal blood
18
2
34
1
1
812448
GSM1437908
wholeblood_812448_2
peripheral maternal blood
30
2
34
2
1
812448
GSM1437909
wholeblood_812459_1
peripheral maternal blood
18
2
34
1
1
812459
GSM1437910
wholeblood_812459_2
peripheral maternal blood
30
2
34
2
1
812459
GSM1437911
wholeblood_812477_1
peripheral maternal blood
20
3
38
1
0
812477
GSM1437912
wholeblood_812477_2
peripheral maternal blood
31
3
38
2
0
812477
GSM1437913
wholeblood_812509_1
peripheral maternal blood
20
3
38
1
0
812509
GSM1437914
wholeblood_812509_2
peripheral maternal blood
30
3
38
2
0
812509
GSM1437915
wholeblood_812518_1
peripheral maternal blood
19
3
37
1
0
812518
GSM1437916
wholeblood_812518_2C
peripheral maternal blood
28
3
37
2
0
812518
GSM1437917
wholeblood_812546_1
peripheral maternal blood
20
3
38
1
0
812546
GSM1437918
wholeblood_812546_2
peripheral maternal blood
30
3
38
2
0
812546
GSM1437919
wholeblood_812551_1
peripheral maternal blood
19
3
40
1
0
812551
GSM1437920
wholeblood_812551_2
peripheral maternal blood
29
3
40
2
0
812551
GSM1437921
wholeblood_812555_1
peripheral maternal blood
19
2
28
1
1
812555
GSM1437922
wholeblood_812559_1
peripheral maternal blood
20
3
38
1
0
812559
GSM1437923
wholeblood_812559_2
peripheral maternal blood
29
3
38
2
0
812559
GSM1437924
wholeblood_812562_1
peripheral maternal blood
19
3
41
1
0
812562
GSM1437925
wholeblood_812562_2
peripheral maternal blood
28
3
41
2
0
812562
GSM1437926
wholeblood_812566_1
peripheral maternal blood
19
2
29
1
1
812566
GSM1437927
wholeblood_812566_2
peripheral maternal blood
29
2
29
2
1
812566
GSM1437928
wholeblood_812573_1
peripheral maternal blood
19
3
39
1
0
812573
GSM1437929
wholeblood_812573_2
peripheral maternal blood
29
3
39
2
0
812573
GSM1437930
wholeblood_812574_1
peripheral maternal blood
20
3
40
1
0
812574
GSM1437931
wholeblood_812574_2
peripheral maternal blood
33
3
40
2
0
812574
GSM1437932
wholeblood_812581_1
peripheral maternal blood
20
3
41
1
0
812581
GSM1437933
wholeblood_812581_2
peripheral maternal blood
28
3
41
2
0
812581
GSM1437934
wholeblood_812586_1
peripheral maternal blood
17
3
41
1
0
812586
GSM1437935
wholeblood_812586_2
peripheral maternal blood
29
3
41
2
0
812586
GSM1437936
wholeblood_812587_1
peripheral maternal blood
18
2
33
1
1
812587
GSM1437937
wholeblood_812587_2
peripheral maternal blood
27
2
33
2
1
812587
GSM1437938
wholeblood_812590_1
peripheral maternal blood
22
3
39
1
0
812590
GSM1437939
wholeblood_812590_2
peripheral maternal blood
31
3
39
2
0
812590
GSM1437940
wholeblood_815072_1
peripheral maternal blood
21
3
37
1
0
815072
GSM1437941
wholeblood_815072_2
peripheral maternal blood
27
3
37
2
0
815072
GSM1437942
wholeblood_815073_1
peripheral maternal blood
18
1
31
1
1
815073
GSM1437943
wholeblood_815073_2
peripheral maternal blood
30
1
31
2
1
815073
GSM1437944
wholeblood_815076_1
peripheral maternal blood
18
2
34
1
1
815076
GSM1437945
wholeblood_815076_2
peripheral maternal blood
31
2
34
2
1
815076
GSM1437946
wholeblood_815082_1
peripheral maternal blood
18
2
26
1
1
815082
GSM1437947
wholeblood_815094_1
peripheral maternal blood
19
3
37
1
0
815094
GSM1437948
wholeblood_815094_2
peripheral maternal blood
28
3
37
2
0
815094
GSM1437949
wholeblood_815102_1
peripheral maternal blood
19
3
38
1
0
815102
GSM1437950
wholeblood_815102_2
peripheral maternal blood
28
3
38
2
0
815102
GSM1437951
wholeblood_815116_1
peripheral maternal blood
19
2
36
1
1
815116
GSM1437952
wholeblood_815116_2
peripheral maternal blood
31
2
36
2
1
815116
GSM1437953
wholeblood_815123_1
peripheral maternal blood
18
3
41
1
0
815123
GSM1437954
wholeblood_815123_2
peripheral maternal blood
28
3
41
2
0
815123
GSM1437955
wholeblood_815127_1
peripheral maternal blood
21
3
39
1
0
815127
GSM1437956
wholeblood_815127_2
peripheral maternal blood
30
3
39
2
0
815127
GSM1437957
wholeblood_815137_1
peripheral maternal blood
20
3
39
1
0
815137
GSM1437958
wholeblood_815137_2
peripheral maternal blood
30
3
39
2
0
815137
GSM1437959
wholeblood_815149_1
peripheral maternal blood
18
2
36
1
1
815149
GSM1437960
wholeblood_815149_2
peripheral maternal blood
31
2
36
2
1
815149
GSM1437961
wholeblood_815154_1
peripheral maternal blood
19
3
39
1
0
815154
GSM1437962
wholeblood_815154_2
peripheral maternal blood
28
3
39
2
0
815154
GSM1437963
wholeblood_815163_1
peripheral maternal blood
21
3
39
1
0
815163
GSM1437964
wholeblood_815163_2
peripheral maternal blood
30
3
39
2
0
815163
GSM1437965
wholeblood_815168_1
peripheral maternal blood
19
3
39
1
0
815168
GSM1437966
wholeblood_815168_2
peripheral maternal blood
29
3
39
2
0
815168
GSM1437967
wholeblood_815179_1
peripheral maternal blood
18
2
33
1
1
815179
GSM1437968
wholeblood_815179_2
peripheral maternal blood
30
2
33
2
1
815179
GSM1437969
wholeblood_815183_1
peripheral maternal blood
20
3
37
1
0
815183
GSM1437970
wholeblood_815183_2
peripheral maternal blood
31
3
37
2
0
815183
GSM1437971
wholeblood_815189_1
peripheral maternal blood
18
3
38
1
0
815189
GSM1437972
wholeblood_815189_2
peripheral maternal blood
28
3
38
2
0
815189
GSM1437973
wholeblood_815194_1B
peripheral maternal blood
21
3
38
1
0
815194
GSM1437974
wholeblood_815194_2
peripheral maternal blood
31
3
38
2
0
815194
GSM1437975
wholeblood_815196_1
peripheral maternal blood
18
3
39
1
0
815196
GSM1437976
wholeblood_815196_2
peripheral maternal blood
28
3
39
2
0
815196
GSM1437977
wholeblood_815200_1
peripheral maternal blood
19
1
30
1
1
815200
GSM1437978
wholeblood_815200_2
peripheral maternal blood
29
1
30
2
1
815200
GSM1437979
wholeblood_815218_1
peripheral maternal blood
19
1
34
1
1
815218
GSM1437980
wholeblood_815218_2
peripheral maternal blood
28
1
34
2
1
815218
GSM1437981
wholeblood_815219_1
peripheral maternal blood
19
3
40
1
0
815219
GSM1437982
wholeblood_815219_2
peripheral maternal blood
30
3
40
2
0
815219
GSM1437983
wholeblood_818022_1
peripheral maternal blood
20
3
41
1
0
818022
GSM1437984
wholeblood_818022_2
peripheral maternal blood
28
3
41
2
0
818022
GSM1437985
wholeblood_818023_1
peripheral maternal blood
22
2
35
1
1
818023
GSM1437986
wholeblood_818023_2
peripheral maternal blood
29
2
35
2
1
818023
GSM1437987
wholeblood_818025_1
peripheral maternal blood
21
3
40
1
0
818025
GSM1437988
wholeblood_818025_2
peripheral maternal blood
28
3
40
2
0
818025
GSM1437989
wholeblood_818032_1
peripheral maternal blood
20
3
37
1
0
818032
GSM1437990
wholeblood_818032_2
peripheral maternal blood
32
3
37
2
0
818032
GSM1437991
wholeblood_818034_1
peripheral maternal blood
19
2
35
1
1
818034
GSM1437992
wholeblood_818034_2
peripheral maternal blood
31
2
35
2
1
818034
GSM1437993
wholeblood_818036_1
peripheral maternal blood
21
3
37
1
0
818036
GSM1437994
wholeblood_818036_2
peripheral maternal blood
28
3
37
2
0
818036
GSM1437995
wholeblood_818046_1
peripheral maternal blood
20
3
40
1
0
818046
GSM1437996
wholeblood_818046_2
peripheral maternal blood
32
3
40
2
0
818046
GSM1437997
wholeblood_818054_1
peripheral maternal blood
19
3
40
1
0
818054
GSM1437998
wholeblood_818054_2
peripheral maternal blood
30
3
40
2
0
818054
GSM1437999
wholeblood_818070_1
peripheral maternal blood
19
3
39
1
0
818070
GSM1438000
wholeblood_818070_2
peripheral maternal blood
29
3
39
2
0
818070
GSM1438001
wholeblood_818081_1
peripheral maternal blood
19
3
39
1
0
818081
GSM1438002
wholeblood_818081_2
peripheral maternal blood
30
3
39
2
0
818081
GSM1438003
wholeblood_818084_1
peripheral maternal blood
19
3
41
1
0
818084
GSM1438004
wholeblood_818084_2
peripheral maternal blood
29
3
41
2
0
818084
GSM1438005
wholeblood_818088_1
peripheral maternal blood
18
3
40
1
0
818088
GSM1438006
wholeblood_818088_2
peripheral maternal blood
28
3
40
2
0
818088
GSM1438007
wholeblood_818125_1
peripheral maternal blood
20
3
39
1
0
818125
GSM1438008
wholeblood_818125_2
peripheral maternal blood
31
3
39
2
0
818125
GSM1438009
wholeblood_818153_1
peripheral maternal blood
18
3
39
1
0
818153
GSM1438010
wholeblood_818153_2A
peripheral maternal blood
28
3
39
2
0
818153
GSM1438011
wholeblood_818156_1
peripheral maternal blood
20
3
41
1
0
818156
GSM1438012
wholeblood_818156_2
peripheral maternal blood
28
3
41
2
0
818156
GSM1438013
wholeblood_818162_1
peripheral maternal blood
18
2
35
1
1
818162
GSM1438014
wholeblood_818162_2
peripheral maternal blood
29
2
35
2
1
818162
GSM1438015
wholeblood_818172_1
peripheral maternal blood
21
3
40
1
0
818172
GSM1438016
wholeblood_818172_2
peripheral maternal blood
29
3
40
2
0
818172
GSM1438017
wholeblood_818174_1
peripheral maternal blood
19
3
38
1
0
818174
GSM1438018
wholeblood_818174_2
peripheral maternal blood
28
3
38
2
0
818174
GSM1438019
wholeblood_818181_1
peripheral maternal blood
20
3
37
1
0
818181
GSM1438020
wholeblood_818181_2
peripheral maternal blood
30
3
37
2
0
818181
GSM1438021
wholeblood_818195_1
peripheral maternal blood
20
2
34
1
1
818195
GSM1438022
wholeblood_818195_2
peripheral maternal blood
31
2
34
2
1
818195
GSM1438023
wholeblood_818200_1
peripheral maternal blood
22
3
40
1
0
818200
GSM1438024
wholeblood_818200_2
peripheral maternal blood
32
3
40
2
0
818200
GSM1438025
wholeblood_818224_1
peripheral maternal blood
18
2
36
1
1
818224
GSM1438026
wholeblood_818224_2
peripheral maternal blood
29
2
36
2
1
818224
GSM1438027
wholeblood_818241_1
peripheral maternal blood
20
2
36
1
1
818241
GSM1438028
wholeblood_818241_2
peripheral maternal blood
32
2
36
2
1
818241
GSM1438029
wholeblood_818246_1
peripheral maternal blood
20
3
39
1
0
818246
GSM1438030
wholeblood_818246_2
peripheral maternal blood
28
3
39
2
0
818246
GSM1438031
wholeblood_818249_1
peripheral maternal blood
21
2
33
1
1
818249
GSM1438032
wholeblood_818249_2
peripheral maternal blood
30
2
33
2
1
818249
GSM1438033
wholeblood_818257_1
peripheral maternal blood
21
3
39
1
0
818257
GSM1438034
wholeblood_818257_2
peripheral maternal blood
30
3
39
2
0
818257
GSM1438035
wholeblood_818308_1
peripheral maternal blood
22
3
39
1
0
818308
GSM1438036
wholeblood_818308_2
peripheral maternal blood
31
3
39
2
0
818308
GSM1438037
wholeblood_818357_1
peripheral maternal blood
21
3
41
1
0
818357
GSM1438038
wholeblood_818357_2B
peripheral maternal blood
30
3
41
2
0
818357
GSM1438039
wholeblood_818361_1i
peripheral maternal blood
20
3
39
1
0
818361
GSM1438040
wholeblood_818361_2A
peripheral maternal blood
28
3
39
2
0
818361
GSM1438041
wholeblood_818368_1
peripheral maternal blood
18
2
36
1
1
818368
GSM1438042
wholeblood_818368_2
peripheral maternal blood
29
2
36
2
1
818368
GSM1438043
wholeblood_818381_1B
peripheral maternal blood
19
3
40
1
0
818381
GSM1438044
wholeblood_818381_2A
peripheral maternal blood
30
3
40
2
0
818381
GSM1438045
wholeblood_818409_1
peripheral maternal blood
22
2
35
1
1
818409
GSM1438046
wholeblood_818409_2
peripheral maternal blood
29
2
35
2
1
818409
GSM1438047
wholeblood_818481_1
peripheral maternal blood
19
2
31
1
1
818481
GSM1438048
wholeblood_818481_2
peripheral maternal blood
29
2
31
2
1
818481
GSM1438049
wholeblood_818614_1A
peripheral maternal blood
19
2
35
1
1
818614
GSM1438050
wholeblood_818614_2C
peripheral maternal blood
28
2
35
2
1
818614
GSM1438051
wholeblood_818615_1
peripheral maternal blood
20
1
36
1
1
818615
GSM1438052
wholeblood_818615_2
peripheral maternal blood
28
1
36
2
1
818615
GSM1438053
wholeblood_818626_1
peripheral maternal blood
23
2
36
1
1
818626
GSM1438054
wholeblood_818626_2
peripheral maternal blood
29
2
36
2
1
818626
GSM1438055
wholeblood_818670_1A
peripheral maternal blood
22
1
33
1
1
818670
GSM1438056
wholeblood_818670_2
peripheral maternal blood
30
1
33
2
1
818670
GSM1438057
wholeblood_818684_1
peripheral maternal blood
20
2
36
1
1
818684
GSM1438058
wholeblood_818684_2
peripheral maternal blood
28
2
36
2
1
818684
GSM1438059
wholeblood_818781_1C
peripheral maternal blood
22
2
35
1
1
818781
GSM1438060
wholeblood_818781_2A
peripheral maternal blood
29
2
35
2
1
818781
GSM1438061
wholeblood_818827_1
peripheral maternal blood
19
2
34
1
1
818827
GSM1438062
wholeblood_818827_2
peripheral maternal blood
29
2
34
2
1
818827
GSM1438063
wholeblood_830347_1B
peripheral maternal blood
20
3
40
1
0
830347
GSM1438064
wholeblood_830347_2
peripheral maternal blood
28
3
40
2
0
830347
GSM1438065
wholeblood_830356_1
peripheral maternal blood
19
3
39
1
0
830356
GSM1438066
wholeblood_830356_2
peripheral maternal blood
30
3
39
2
0
830356
GSM1438067
wholeblood_830370_1
peripheral maternal blood
19
3
40
1
0
830370
GSM1438068
wholeblood_830370_2
peripheral maternal blood
31
3
40
2
0
830370
GSM1438069
wholeblood_830381_1
peripheral maternal blood
20
3
40
1
0
830381
GSM1438070
wholeblood_830381_2
peripheral maternal blood
29
3
40
2
0
830381
GSM1438071
wholeblood_830397_1
peripheral maternal blood
20
1
36
1
1
830397
GSM1438072
wholeblood_830397_2
peripheral maternal blood
29
1
36
2
1
830397
GSM1438073
wholeblood_830398_1
peripheral maternal blood
19
2
34
1
1
830398
GSM1438074
wholeblood_830398_2
peripheral maternal blood
28
2
34
2
1
830398
GSM1438075
wholeblood_830432_1
peripheral maternal blood
18
3
39
1
0
830432
GSM1438076
wholeblood_830432_2
peripheral maternal blood
28
3
39
2
0
830432
GSM1438077
wholeblood_830446_1
peripheral maternal blood
20
1
36
1
1
830446
GSM1438078
wholeblood_830446_2
peripheral maternal blood
29
1
36
2
1
830446
GSM1438079
wholeblood_830478_1
peripheral maternal blood
19
3
38
1
0
830478
GSM1438080
wholeblood_830478_2
peripheral maternal blood
28
3
38
2
0
830478
GSM1438081
wholeblood_830505_1
peripheral maternal blood
19
2
31
1
1
830505
GSM1438082
wholeblood_830505_2
peripheral maternal blood
28
2
31
2
1
830505
GSM1438083
wholeblood_830507_1
peripheral maternal blood
18
3
39
1
0
830507
GSM1438084
wholeblood_830507_2
peripheral maternal blood
30
3
39
2
0
830507
GSM1438085
wholeblood_830515_1
peripheral maternal blood
19
3
38
1
0
830515
GSM1438086
wholeblood_830515_2
peripheral maternal blood
29
3
38
2
0
830515
GSM1438087
wholeblood_830518_1
peripheral maternal blood
19
3
39
1
0
830518
GSM1438088
wholeblood_830518_2
peripheral maternal blood
29
3
39
2
0
830518
GSM1438089
wholeblood_830538_1
peripheral maternal blood
20
3
40
1
0
830538
GSM1438090
wholeblood_830538_2
peripheral maternal blood
31
3
40
2
0
830538
GSM1438091
wholeblood_830544_1
peripheral maternal blood
18
3
40
1
0
830544
GSM1438092
wholeblood_830544_2
peripheral maternal blood
31
3
40
2
0
830544
GSM1438093
wholeblood_830554_1C
peripheral maternal blood
18
3
39
1
0
830554
GSM1438094
wholeblood_830554_2A
peripheral maternal blood
29
3
39
2
0
830554
GSM1438095
wholeblood_830560_1
peripheral maternal blood
19
1
34
1
1
830560
GSM1438096
wholeblood_830560_2
peripheral maternal blood
31
1
34
2
1
830560
GSM1438097
wholeblood_830561_1
peripheral maternal blood
19
3
39
1
0
830561
GSM1438098
wholeblood_830561_2
peripheral maternal blood
29
3
39
2
0
830561
GSM1438099
wholeblood_830575_1
peripheral maternal blood
20
3
38
1
0
830575
GSM1438100
wholeblood_830575_2
peripheral maternal blood
31
3
38
2
0
830575
GSM1438101
wholeblood_830576_1
peripheral maternal blood
19
3
40
1
0
830576
GSM1438102
wholeblood_830576_2A
peripheral maternal blood
31
3
40
2
0
830576
GSM1438103
wholeblood_830584_1
peripheral maternal blood
19
3
39
1
0
830584
GSM1438104
wholeblood_830584_2
peripheral maternal blood
30
3
39
2
0
830584
GSM1438105
wholeblood_830587_1
peripheral maternal blood
19
3
41
1
0
830587
GSM1438106
wholeblood_830587_2
peripheral maternal blood
31
3
41
2
0
830587
GSM1438107
wholeblood_830590_1
peripheral maternal blood
19
1
36
1
1
830590
GSM1438108
wholeblood_830590_2
peripheral maternal blood
30
1
36
2
1
830590
GSM1438109
wholeblood_830597_1
peripheral maternal blood
19
3
39
1
0
830597
GSM1438110
wholeblood_830597_2A
peripheral maternal blood
30
3
39
2
0
830597
GSM1438111
wholeblood_830607_1
peripheral maternal blood
19
3
40
1
0
830607
GSM1438112
wholeblood_830607_2
peripheral maternal blood
29
3
40
2
0
830607
GSM1438113
wholeblood_830656_1
peripheral maternal blood
19
3
40
1
0
830656
GSM1438114
wholeblood_830656_2
peripheral maternal blood
32
3
40
2
0
830656
GSM1438115
wholeblood_830692_1
peripheral maternal blood
20
3
38
1
0
830692
GSM1438116
wholeblood_830692_2
peripheral maternal blood
29
3
38
2
0
830692
GSM1438117
wholeblood_830741_1
peripheral maternal blood
18
3
39
1
0
830741
GSM1438118
wholeblood_830741_2
peripheral maternal blood
28
3
39
2
0
830741
GSM1438119
wholeblood_830762_1
peripheral maternal blood
21
2
35
1
1
830762
GSM1438120
wholeblood_830762_2
peripheral maternal blood
29
2
35
2
1
830762
GSM1438121
wholeblood_830790_1
peripheral maternal blood
21
2
34
1
1
830790
GSM1438122
wholeblood_830790_2
peripheral maternal blood
30
2
34
2
1
830790
GSM1438123
wholeblood_830872_1A
peripheral maternal blood
19
2
34
1
1
830872
GSM1438124
wholeblood_830872_2A
peripheral maternal blood
29
2
34
2
1
830872
GSM1438125
wholeblood_830909_1
peripheral maternal blood
18
2
35
1
1
830909
GSM1438126
wholeblood_830909_2
peripheral maternal blood
32
2
35
2
1
830909

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